Polyacrylonitrile modified with hydrogen halide for immobilizati

Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;... – Enzyme or microbial cell is immobilized on or in an organic...

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435803, 436531, 5253291, 530413, 530815, C12N 1108, G01N 33545, C08F 2044, C07K 320

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active

052623173

ABSTRACT:
Polyacrylonitrile is chemically modified with HX (Cl, Br, I, CF.sub.3 SO.sub.3 H) to produce a polymer with readily replaceable X groups. The modified polyacrylonitrile is useful as an immobilization substrate for, e.g., proteins and in affinity chromatography

REFERENCES:
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patent: 4371612 (1983-02-01), Matsumoto et al.
patent: 4486549 (1984-12-01), Matsumoto et al.
patent: 4705753 (1987-11-01), Gregor et al.
A. L. Endrey, "The Base-Catalyzed Transformation of Polyacrylonitrile," Journal of Polymer Science: Polymer Chemistry Edition, vol. 20, pp. 2105-2116 (1982).
Handa et al., "The Effect of Methlacrylate on the Activity of Glucoamylase Immobilization on Granular Polyacrylonitrile," Biotechnology and Bioengineering, vol. XXIV, pp. 1639-1652 (1982).
Okamoto et al., "Effect of Hydrogen Chloride on Thermal Degradation of Polyacrylonitrile," J. Chem. Soc. Japan, No. 4, pp. 566-570 (1983).

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