Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1980-08-04
1981-11-24
Roberts, Elbert L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
424180, 424309, 424311, 424330, 424301, 424329, 424252, 424308, 424324, 424274, 424267, 424279, 26039745, A61K 31705, C07J 4100, A61K 31505
Patent
active
043024572
ABSTRACT:
This invention relates to a new method of therapy comprising the administration of a pro-drug to a human or animal, said pro-drug being a compound formed by a therapeutic compound chemically combined with another moiety by a photocleavable bond and irradiating the diseased area with ultraviolet radiation in an amount sufficient to cleave the bond and release the therapeutic compound in a therapeutically effective amount. Specifically disclosed are pro-drugs which are cleaved to therapeutically active medications which are anti-proliferative and anti-inflammatory compounds and the treatment of inflammatory and/or proliferative skin diseases therewith.
REFERENCES:
patent: 4162316 (1979-07-01), Nishimura et al.
patent: 4166116 (1979-08-01), Coutts et al.
patent: 4224325 (1980-09-01), Szilagyi et al.
Voorhees John J.
Wierenga Wendell
Killinger John J.
Roberts Elbert L.
The Regents of the University of Michigan
The Upjohn Company
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