Dimeric naphthylisoquinoline alkaloids and synthesis methods the

Details Dimeric naphthylisoquinoline alkaloids and synthesis methods the Dimeric naphthylisoquinoline alkaloids and synthesis methods the

1994-07-22

1996-11-05

Davis, Zinna Northington

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546139, 546140, 546147, C07D21702, C07D21704

Patent

active

055719198

ABSTRACT:
The present invention provides methods of preparing dimeric naphthylisoquinoline alkaloids by coupling together two monomeric naphthylisoquinoline alkaloids, each of which may be the same or different, and one, both, or neither of which may possess a C-8' to C-5 naphthalene/isoquinoline linkage, to form homodimers or heterodimers, including the antiviral michellamines. The present invention also provides new, medically useful homodimeric and heterodimeric naphthylisoquinoline compounds and derivatives thereof.

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