Method for preparation of monosialoganglioside GM1

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435 74, 4352533, 435874, C12P 1944, C12P 1926, C12P 1900

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active

057563144

ABSTRACT:
A method for producing monosialoganglioside GM1 comprising the step of contacting a crude ganglioside mixture with a microorganism capable of producing a sialidase; and a bacterial strain of Pseudomonas genus capable of producing a sialidase and usable in the above method.

REFERENCES:
patent: 4868292 (1989-09-01), Yokoyama et al.
patent: 5275939 (1994-01-01), Sugimori et al.
patent: 5296360 (1994-03-01), Sugimori et al.
Julian N. Kanfer, Methods in Enzymology, Preparation of Gangliosides, vol. 14, pp. 660-664 (1969).
Robert W. Ledeen et al., Methods in Enzymology, Gangliosides: Structure, Isolation . . . , 83, pp. 139-191.
APS Abstract JP63-291582 Morikawa et al (Nov. 29, 1985).

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