Tetrahydro-cyclopenta[.beta.]furanes

Details Tetrahydro-cyclopenta[.beta.]furanes Tetrahydro-cyclopenta[.beta.]furanes

1985-09-09

1987-05-12

Milestone, Norma S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07F 702

Patent

active

046651985

ABSTRACT:
The prostacyclins 7-fluoro-6,9-epoxy-16-substituted-15-hydroxyprost-[4 or 5,13]-dienoic acids and esters useful as anti-secretory agents, blood pressure lowering agents, anti-ulcerogenic agents, anti-hypertensive agents, bronchodilation agents and for combating gastro-hyperacidity and as anti-blood platelet aggregating agents.

REFERENCES:
patent: 4456768 (1984-06-01), Fried
patent: 4472428 (1984-09-01), Toru et al.
Fried et al., J. Med. Chem., 1980, 23, pp. 234-237.
Sukenick, J. Am. Chem. Soc. 1976, 98, p. 6613.
Corey et al., J. Am. Chem. Soc., 1977, 99, pp. 2006-2007.

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