Derivatives of isoxazolo[4,5-c]quinoline(2H)-3-one and method of

Details Derivatives of isoxazolo[4,5-c]quinoline(2H)-3-one and method of Derivatives of isoxazolo[4,5-c]quinoline(2H)-3-one and method of

1985-06-21

1986-05-13

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 83, 546153, A61K 3142, C07D49802, C07D21500

Patent

active

045887314

ABSTRACT:
Novel isoxazoloquinolinones of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, fluorine, chlorine, bromine, alkyl and alkoxy of 1 to 5 carbon atoms, --NO.sub.2 and CF.sub.3 -- and R.sub.1 is phenyl optionally substituted by at least one member selected from the group consisting of halogen and alkyl and alkoxy of 1 to 5 carbon atoms having anxiolytic activity and their preparation and novel intermediates.

REFERENCES:
Fiese, L. F., Reagents for Organic Synthesis, 1967, pp. 478-479.

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