Compositions and methods for the identification and synthesis of

Details Compositions and methods for the identification and synthesis of Compositions and methods for the identification and synthesis of

1993-08-04

1999-10-05

Wax, Robert A.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

435 691, 4352523, 536 231, 536 221, 536 232, 536 235, C12N 910

Patent

active

059622946

ABSTRACT:
DNA isolates coding for sialyltransferase which contain a conserved region of homology and methods of obtaining such DNA are provided, together with expression systems for recombinant production of sialyltransferase.

REFERENCES:
Sadler et al., "Purification to Homogeneity of a beta-Galactoside alpha2-3 Sialytransferase . . . ", Journal of Biological Chemistry, vol. 254, No. 11, pp. 4434-4443 (1979).
Weinstein et al., "Purification of a Galbeta 1-4GlcNAc alpha2-6 Sialytransferase . . . ", Journal of Biological Chemistry, vol. 267, No. 22, pp. 13835-13844 (1962).
Nemansky et al., "Human liver and human placenta both contain CMP-NeuAc:Galbeta 1-4GlcNAc-R alpha2-3 . . . ", FEBS vol. 312, No. 1 pp. 31-36 Nov. (1992).
Mathews et al., "Mass Spectrometrically Derived . . . ", Journal of Biological Chemistry, vol. 262, No. 16, pp. 7537-7545 (1987).
Lee et al., "Generation of cDNA Probed Directed by Amino Acid Sequence . . . ", Science vol. 239, pp. 1288-1291 (1988).

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