Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1998-01-08
1999-10-05
Carlson, Karen Cochrane
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352523, 435325, 4353201, 536 231, 530350, C12P 2106, C12N 1500, C07H 1700, C07K 1400
Patent
active
059622636
ABSTRACT:
The invention provides human membrane recycling proteins (HMRP) and polynucleotides which identify and encode HMRP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HMRP.
REFERENCES:
Sudhof, T.C. and Jahn, R. "Proteins of Synaptic Vesicles Involved in Exocytosis and Membrane Recycling" Neuron (1991) 6:665-677.
Sudhof, T.C. et al., "Membrane Fusion Machinery: Insights from Synaptic Proteins" Cell (1993) 75:1-4.
Brand, S.H. et al., "Secretory Carrier Membrane Proteins 31-35 Define a Common Protein Composition among Secretory Carrier Membranes" J.Biol.Chem. (1991) 266:18949-18957.
Brand, S.H. and Castle, J.D. "SCAMP 37, a new marker within the general cell surface recycling system" EMBO J. (1993) 12:3753-3761.
Laurie, S.M. et al., "The Glucose Transporter GluT4 and Secretory Carrier Membrane Proteins (SCAMPs) Colocalize in Rat Adipocytes and Partially Segregate during Insulin Stimulation" J.Biol.Chem. (1993) 25:19110-19117.
Brand, S.H. and Castle, J.D. (GI 487057), GenBank Sequence Database (Accession S37395), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894.
Wu, T.T. and Castle, J.D. "Evidence for colocalization and interaction between 37 and 39 kDa isoforms of secretory carrier membrane proteins (SCAMPs)" J.Cell Science (1997) 110:1533-1541.
Singleton, D.R. et al., (GI 2232243) GenBank Sequence Database (Accession AF005039), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894.
Singleton, D.R. et al., (GI 2232241) GenBank Sequence Database (Accession AF005038), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894.
Singleton, D.R. et al., "Three mammalian SCAMPs (secretory carrier membrane proteins) are highly related proteins of distinct genes having similar subcellular distributions" J.Cell Science (1997) 110:2099-2107.
Corley Neil C.
Lal Preeti
Shah Purvi
Carlson Karen Cochrane
Incyte Pharmaceuticals Inc.
Mohan-Peterson Sheela
Muenzen Colette C.
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