Optics: measuring and testing – By dispersed light spectroscopy
Patent
1993-03-19
1996-08-27
Hille, Rolf
Optics: measuring and testing
By dispersed light spectroscopy
356319, 356320, G01J 300, G01J 342, G01J 3427
Patent
active
055506305
ABSTRACT:
A method for analyzing the structures of chemical organic compounds, polymers, polynucleotides and peptides is disclosed. The method uses the integrated intensity of spectral light absorption in wide or narrow regions of the ultraviolet and/or visible spectrum and relates these parameters additively to the structural characteristics of the analyzed chemical compound. For the analysis of polymers, nucleotides and/or peptides the integrated intensities of spectral absorption are used sequentially in narrow regions of the ultraviolet light which enables the determination of the molecular weight and the complete amino acid composition of the analyzed compound. All these procedures are interconnected in an automatic spectrophotometric structural analyzer.
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Chrastill, Joseph, "A Group Additivity Model for Analyzing Absorption Spectra of Organic Compounds: Applications to Partial Structural Analysis and Molecular Weight Determinations of Polymers, Nucleotides, and Peptides", Analytical Biochemistry, 202, 1992, pp. 126-145.
Deck Randall E.
Fado John D.
Hille Rolf
Ostrowski David
Silverstein M. Howard
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