Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1973-08-02
1976-11-30
Rizzo, Nicholas S.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
2602391, 424271, 260243C, 424246, C07D49904, C07D50102
Patent
active
039949117
ABSTRACT:
Novel 6-APA, 7-ACA, and 7-ADCA derivatives are described which comprise phosphorylated derivatives of 6-APA, 7-ACA, or 7-ADCA and the corresponding acylated derivatives thereof. The novel compounds are prepared by the reaction of 6-APA, 7-ACA, 7-ADCA or a salt thereof with a phosphorus halide in the presence of an acid acceptor and subsequently acylating the thus formed phosphorylated compound, to form a phosphorylated acylated derivative which upon hydrolysis with water splits off the protective group(s) to provide the corresponding semi-synthetic penicillin or cephalosporin having useful antibacterial activity.
REFERENCES:
patent: 3809699 (1974-05-01), Ishimaru
American Home Products Corporation
Rizzo Nicholas S.
LandOfFree
Intermediate for producing semi-synthetic penicillins and cephal does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Intermediate for producing semi-synthetic penicillins and cephal, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Intermediate for producing semi-synthetic penicillins and cephal will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1054699