Method of producing analgesia

Details Method of producing analgesia Method of producing analgesia

1996-09-13

2000-12-26

MacMillan, Keith

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514817, 424253, 42424854, 424267, A61K 3152

Patent

active

06166085&

ABSTRACT:
The invention relates to methods of producing analgesia, particularly in the treatment-of-acute and persistent pain and neuropathic pain. The compound 2(ethylamino)-N-(3-hydroxy-2,6-dimethylphenyl) acetamide, or 3-hydroxymonoethylglycinexylidide (3-hydroxy MEGX), is shown to provide analgesia in settings of acute, persistent and neuropathic pain.

REFERENCES:
patent: 3689555 (1972-09-01), Schut et al.
patent: 4001413 (1977-01-01), Adams et al.
patent: 4532249 (1985-07-01), Molnar et al.
patent: 5496854 (1996-03-01), Keinan
Abu-Shady, H., et al., "Synthesis of some 4-aminophenol derivatives of expected pharmacodynamic activity", Chemical Abstracts, Abstract No. 477795 (1976) [Egypt. J. Pharm. Sci., 16(3):289-96 (1976)].

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