Process for making high purity piperine for nutritional use

Details Process for making high purity piperine for nutritional use Process for making high purity piperine for nutritional use

1998-12-23

2000-04-25

Chang, Ceila

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514321, C07D40706

Patent

active

060545852

ABSTRACT:
The present invention relates to a process of making high purity piperine for nutritional and nutraceutical application. This process recovers piperine from piperine-containing oleoresin by using isourea, urea or a urea derivative to remove organic matter other than piperine from the oleoresin. Preferrably, the process recovers piperine from oleoresin of fruit of piper nigrum or piper longum. More preferably, the process recovers piperine from oleoresin of fruit of piper nigrum, i.e. black pepper.

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Windholz et al. Merck Index, 9th ed. p. 972, 1976.
Graham Reaction of Piperine with nitric acid. J. Phar. Sci. v. 54 (2) p. 319-321, Feb. 1965.
Tabuneng et al. "Studies on the constituents of the crude drug piperis longi fructus" Chem. Phar. Bull. vo. 31 (10) p. 3562-65, Oct. 1983.

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