Isolation and characterization of cDNAs coding for the .alpha.,

Details Isolation and characterization of cDNAs coding for the .alpha., Isolation and characterization of cDNAs coding for the .alpha.,

1990-12-14

2000-12-26

Ulm, John

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4352523, 4353201, 530350, 536 235, C07K 14705, C12N 1512

Patent

active

061657441

ABSTRACT:
The present invention relates to DNA segments encoding the .alpha., .beta., and .gamma. subunits of the high affinity receptor for immunoglobulin E (IgE). The invention further relates to a method of producing the receptor by expressing cDNA for its .alpha., .beta., and .gamma. subunits in a host cell simultaneously.

REFERENCES:
Am. Rev. Immunol. 4:419-430, 1986, Metzger et al. The Receptor with High Affinity for Immunoglobulin E.
Nature 313:806-809, Feb. 28, 1985, Jacoby et al. Isolation and Characterization of Genome and cDNA Clones of Human Erythropoietic.
Biochem. 24: 4117-24, 1985, Kinet et al. Dissociation of the Receptor for Immunoglobulin E in Mild Detergents.
Biochemistry 24:7342-48, 1985, Kinet et al. Noncovalently and Covalently Bound Lipid on the Receptor for Immunoglobulin E.
J. Biol. Chem. 259:14922-27, Alcaraz et al. Phase Separation of the Receptor for Immunoglobulin E and Its Subunits in Triton X-114.

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