Methods of inhibiting bone loss

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

Other Related Categories

514424, A61K 31425

Type

Patent

Status

active

Patent number

054768659

Description

ABSTRACT:
Rhodanine derivatives are utilized as inhibitors of bone loss/bone resorption and cartilage degradation.

REFERENCES:
patent: 5158966 (1992-10-01), Lafferty et al.
patent: 5356917 (1994-10-01), Panetta
Christiansen, "Prevention and Treatment of Osteoporosis: A Review of Current Modalities", Bone, 13, 535-539 (1992).
Blair et al., "Isolated Osteoclasts Resorb the Organic and Inorganic Components of Bone," The Journal of Cell Biology, 102, 1164-1172 (Apr. 1986).

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