Novel thione dopamine beta hydroxylase inhibitors

Details Novel thione dopamine beta hydroxylase inhibitors Novel thione dopamine beta hydroxylase inhibitors

1987-10-27

1991-10-15

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D40906

Patent

active

050576135

ABSTRACT:
Imidazole-2-thione derivatives useful as antihypertensive agents are described herein. The compounds are obtained by cyclization of an appropriate open-chain compound such as an appropriately substituted thiourea.

REFERENCES:
patent: 3915980 (1975-10-01), Gebert et al.
patent: 4634711 (1987-01-01), Kaiser et al.
patent: 4749717 (1988-05-01), Kouse
Lawrence I. Kruse, et al., J. Med. Chem., 29,887-889 (1986).
Belgodere, Heterocycles, 20, 2019 (1983).
Stephen T. Ross, et al., J. Med. Chem., 30, 1309-1313 (1987).

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