Film-coated tablet for improved upper gastrointestinal tract saf

Details Film-coated tablet for improved upper gastrointestinal tract saf Film-coated tablet for improved upper gastrointestinal tract saf

1998-06-10

2000-12-26

Celsa, Bennett

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424451, 424456, 424457, 424461, 424464, 424468, 424474, 424475, 424486, 424489, 514108, 514960, 514961, 514962, 514963, 514964, A61K 916, A61K 950

Patent

active

061655139

ABSTRACT:
A novel oral dosage to be delivered to the stomach comprising a safe and effective amount of an active ingredient selected from the group consisting of emepronium bromidebromide, doxycycline, and other tetracyclines/antibiotics, iron preparations, quinidine, nonsteroidal anti-inflammatory drugs, alprenolol, ascorbic acid, captopril, theophylline, zidovoudine (AZT), bisphosphonates and mixtures thereof and pharmaceutically-acceptable excipients, wherein said oral dosage form is a generally oval form and film coated to facilitate rapid esophageal transit and avoid irritation in the mouth, buccal cavity, pharynx, and esophagus.

REFERENCES:
patent: 4302440 (1981-11-01), John et al.
patent: 5096717 (1992-03-01), Wirth et al.
patent: 5146730 (1992-09-01), Sadek et al.
patent: 5431920 (1995-07-01), Bechard
patent: 5622721 (1997-04-01), Dansereau et al.
patent: 5658589 (1997-08-01), Parekh et al.
Seitz, J.A., Mehta, S.P., Yeager, J.L., "Table Coating", The Theory and Practice of Industrial Pharmacy, 3.sup.rd Edition, pp. 346-373, (1986).

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