Esterification process

Details Esterification process Esterification process

1985-08-09

1986-09-30

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 19, 560 45, C07C 6976

Patent

active

046148302

ABSTRACT:
An improvement in the process for esterification of 3,4-dihydroxyphenyl N-alkylaminoalkyl ketones with arylcarboxylic acid chlorides which comprises carrying out the esterification in the presence of a catalytic amount of a 4-di-lower-alkylaminopyridine or 4-(1-pyrrolidinyl)pyridine and an acid-acceptor comprising a tertiary amine or sterically-hindered secondary amine.

REFERENCES:
patent: 3904671 (1975-09-01), Minatoya et al.
patent: 4035404 (1977-07-01), Bodor et al.
patent: 4105787 (1978-08-01), Jones et al.
patent: 4138581 (1979-02-01), Minatoya et al.
patent: 4503256 (1985-03-01), Fourie et al.
Tullar, B. et al. J. Med. Chem. 19(6) 834-8 1976.
Dooley, D. et al. Eur. J. Pharmacol. 70(2) 213-18 1981.
G. Hofle, W. Steglich and H. Vorbruggen, Angew. Chem. Int. Ed. Engl. 17, 569-583 (1978).

Affiliated with

Also associated with

Rating

Esterification process does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Esterification process, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Esterification process will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-985734