Preparation of 4-phenyl-1,3-benzodiazepins

Details Preparation of 4-phenyl-1,3-benzodiazepins Preparation of 4-phenyl-1,3-benzodiazepins

1982-11-12

1984-07-24

Chan, Nicky

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

564373, C07D24303

Patent

active

044617283

ABSTRACT:
The invention relates to compounds of the formula ##STR1## where Y is --OH; halogen; ##STR2## where R.sub.1 is a straight chain or branched chain alkyl group having 1 to 5 carbon atoms, or aryl; and R.sub.2 is --C(CH.sub.3).sub.3 or --O--C(CH.sub.3).sub.3. Processes for preparing the compounds are provided. The compounds are useful as intermediates in the preparation of 4-phenyl-1,3-benzodiazepins, which exhibit activity as antidepressants, analgetics and anticonvulsants.

REFERENCES:
patent: 4182760 (1980-01-01), Middleton
patent: 4409145 (1983-10-01), Martin et al.
Fuhrer et al., J. Org. Chem., 44, 1133, (1979).
Ibid, 45, 4798, (1980), Muchowski et al.

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