Androstanes

Details Androstanes Androstanes

1978-09-26

1980-04-08

Roberts, Elbert L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

26023955C, 26023955R, 2603975, 2603973, 26039745, C07J 7100, A61K 3158

Patent

active

041972961

ABSTRACT:
Steroids of the androstane series are described which possess a 3.alpha.-hydroxy group, a 5.alpha.- or 5.beta.- hydrogen atom, a 10- methyl group, an 11.alpha.- substituted amino group. The 17-position may be unsubstituted or substituted by a methyl or ethyl group in the .beta.-configuration or by an oxo group, or there may be a 16.beta., 17.beta.-epoxide group. A 2.beta.-alkoxy group may optionally be present.
The compounds, particularly their salts, have anaesthetic activity.

REFERENCES:
patent: 3033855 (1962-05-01), Berg et al.
patent: 3869451 (1975-03-01), Phillipps et al.
patent: 3943124 (1976-03-01), Phillipps et al.
patent: 3983111 (1976-09-01), Phillipps et al.
Pelah et al., "JACS," (1965) 87 (3), pp. 574-580.
Marples, "J. Chem. Soc.," Perkin Trans I (1974), pp. 2219-2225, No. 19.

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