Dosage forms having zero-order dihydropyridine calcium antagonis

Details Dosage forms having zero-order dihydropyridine calcium antagonis Dosage forms having zero-order dihydropyridine calcium antagonis

1993-02-08

1995-08-08

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424465, 424480, 424482, 424456, 424457, 424488, A61K 922, A61K 936, A61K 952

Patent

active

054396875

ABSTRACT:
Pharmaceutical dosage forms having a linear release rate of the 0.sup.th order for the once-daily oral administration of 20-120 mg of nifedipine or of another calcium antagonist of the dihydropyridine type, characterised by a homogeneous matrix containing 2-50% by weight of hydroxypropylmethylcellulose having an average molecular weight of 20,000-250,000, 5-60% by weight of a calcium antagonist of the dihydropyridine type, as well as customary excipients compatible with the formulation, such as lipophilic or hydrophilic liberation controllers, fillers, flow-regulating agents, lubricants and, optionally, film coatings.

REFERENCES:
patent: 4412986 (1983-11-01), Kawata et al.
patent: 4571333 (1986-02-01), Hsiao et al.
patent: 4654206 (1987-03-01), Okuda et al.
patent: 4695467 (1987-09-01), Uemura et al.
patent: 4803079 (1989-02-01), Hsiao et al.
patent: 4871548 (1989-10-01), Edgren et al.
patent: 4880623 (1989-11-01), Piergiornio et al.
patent: 4893393 (1983-06-01), Schor et al.
patent: 4942040 (1990-07-01), Ragnarsson et al.
patent: 4966772 (1990-10-01), Ohm et al.
patent: 5055306 (1991-10-01), Barry et al.
patent: 5079237 (1992-01-01), Husu et al.

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