Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1999-08-04
2000-12-05
Ambrose, Michael G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
560 30, 560137, 560159, C07D24106, C07D26906
Patent
active
061568953
ABSTRACT:
An improved process using chiral hydrogenation is described for the synthesis in high yields of a 4-protected-(S)-piperazine-2-tert-butylcarboxamide, an intermediate for an HIV protease inhibitor.
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Pye Philip J.
Reider Paul J.
Rossen Kai
Volante Ralph P.
Ambrose Michael G.
Merck & Co. , Inc.
Walton Kenneth R.
Winokur Melvin
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