Piperidinoalkyl derivatives of carboxylic acid amides

Details Piperidinoalkyl derivatives of carboxylic acid amides Piperidinoalkyl derivatives of carboxylic acid amides

1989-02-06

1992-12-08

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514248, 514252, 514256, 514258, 514259, 514260, 514269, 514272, 514274, 514275, 514318, 514319, 514320, 514321, 514322, 514323, 514324, 514326, 544235, 544237, 544238, 544253, 544297, 544298, 544299, 544301, 544302, 544303, 544305, 544306, 544309, 544311, 544312, 544313, 544314, 544315, 544316, 544317, 544318, 544319, 544321, 544322, 544323, 544325, 544326, 544327, 544329, 544330, 544332, 544333, 544334, 544335, 546194, 546198, 546199, 546200, 546201, 546202, 546205, 546208, 546209, 546210, 546211, 546213,

Patent

active

051698560

ABSTRACT:
The present invention relates to unsaturated carboxylic acid amide derivatives of the formula ##STR1## wherein ring A stands for an optionally substituted aromatic ring; R.sup.1 stands for a hydrogen atom or an optionally substituted hydrocarbon residue or forms an optionally substituted carbocyclic ring with the adjacent group --CH.dbd.C-- together with two carbon atoms constituting the ring A; R.sup.2 stands for a hydrogen atom, an optionally substituted hydrocarbon residue or an optionally substituted acyl group; R.sup.3 stands for an optionally substituted hydrocarbon residue; and n denotes an integer ranging from 2 to 6, and salts thereof, as well as the production thereof.
The compounds of the present invention act on the central nervous system of mammals and has a strong anti-cholinesterase activity, which can be used for the prophylaxis and therapy of, for example, senile dementia, Alzheimer's diseases, Huntington's chorea, et., and are useful as medicines.

REFERENCES:
patent: 4189495 (1980-02-01), Kaplan et al.
patent: 4357337 (1982-11-01), Dubroeucq et al.

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