Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1988-05-12
1990-08-07
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540202, C07D50146, A61K 31545
Patent
active
049468375
ABSTRACT:
A compound of the formula; ##STR1## wherein R.sup.0 stands for nitrogen-containing heterocyclic group, acyl group or amino-protecting group, Z stands for S, S.fwdarw.O, O or CH.sub.2, R.sup.4 stands for hydrogen atom, methoxy group or formamido group, R.sup.13 stands for hydrogen atom, methyl group, hydroxyl group or halogen atom and A stands for an optionally substituted thiazol-3-yl group forming a fused ring at the 4,5-position or a physiologically or pharmaceutically acceptable salt or ester thereof.
This compound is novel and has excellent antibacterial activity.
REFERENCES:
patent: 4564676 (1986-01-01), Nakazawa et al.
patent: 4665066 (1987-05-01), Morin, Jr.
Chemical Abstracts, Biomolecules, Teraji Tsutomu, 97:127387q, "Cephem Compounds", Oct. 11, 1982.
Fujino Masahiko
Kondo Masahiro
Miyake Akio
Rizzo Nicholas S.
Takeda Chemical Industries Ltd.
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