Iodine-containing germicidal preparations and method of controll

Drug – bio-affecting and body treating compositions – Lymphokine

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424667, A61K 3336

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active

049466739

ABSTRACT:
Iodine-containing germicidal preparations are provided with assured control of the content of equilibrium iodine in aqueous solution to be between 1 and 20 ppm, preferably 2-15 ppm so as to provide predetermined germicidal activity. The invention further comprises the determination of the content of equilibrium iodine in an aqueous iodophor solution by subjecting such solution to several extractions with different amounts of a water immiscible solvent for iodine, determining the concentrations of the equilibrium iodine in each of the amounts of the water immiscible solvent and extrapolating the concentration to a theoretical zero value which is a measure of the equilibrium iodine in the aqueous iodophor solution. The invention further comprises improved germicidal iodophor compositions comprising an iodophor, citric acid and iodate.

REFERENCES:
patent: 3355386 (1967-11-01), Cantor
patent: 4045364 (1977-08-01), Richter
patent: 4113857 (1978-09-01), Shetty
patent: 4148884 (1979-04-01), Thorogood
patent: 4271149 (1981-06-01), Winicov et al.

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