Method of preparing phosphodiesterase IV inhibitors

Details Method of preparing phosphodiesterase IV inhibitors Method of preparing phosphodiesterase IV inhibitors

1997-04-02

1998-03-17

Morris, Patricia L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546330, 546335, 546337, 546338, 546340, 546341, 546342, C07D21338, C07D21330, C07D21326, C07D21324

Patent

active

057288380

ABSTRACT:
A process for the preparation of a compound of structural formula I ##STR1## wherein R.sup.1 is alkyl, alkenyl, phenyl or substituted phenyl, which comprises the addition of R.sup.1 to an intermediate 2: ##STR2## by treatment of 2 with (R.sup.1).sub.3 M followed by reductive removal of the sulfinyl group.

REFERENCES:
patent: 5622977 (1997-04-01), Werrellow et al.

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