Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1982-10-25
1984-04-17
Raymond, Richard
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
42424854, 42424855, 424250, 424258, 544101, 544105, 544344, 544353, 546 94, 546165, 546166, 546167, 546173, 548563, 564210, 564221, 564441, 568325, A61K 3147, C07D45504, C07D49816
Patent
active
044434472
ABSTRACT:
Antimicrobial compounds of the following formula are disclosed: ##STR1## wherein X is selected from the group consisting of --O--, --CH.sub.2 and ##STR2## m is 0 or 1; R.sub.1 is selected from the group consisting of hydrogen, nitro, amino, lower alkyl, lower alkanamido, lower N,N-dialkylamino, formamido, hydroxy, lower alkoxy, halogen, lower haloalkanamido and pyrryl; n is 1 or 2; and R.sub.2 is selected from the group consisting of hydrogen, methyl, fluoro, chloro and nitro. Acyl chlorides, esters, alkylaminoalkyl ester salts, amides and pharmaceutically acceptable carboxylate salts are also disclosed. Pharmaceutical compositions containing these compounds, methods of using these compound and synthetic intermediates are also disclosed.
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patent: 4400386 (1983-08-01), Stern
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Japanese Laid-Open Patent Application No. 57-88182, together with a non-certified translation.
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Copy of Abstract Identified as 22102 E/12*BE-891-046.
Otsuka Chemical Abstract Identified as 94:109361K and Related Chemical Abstract Index Listing.
Gerster John F.
Stern Richard M.
Raymond Richard
Riker Laboratories Inc.
Sell Donald M.
Smith James A.
Sprague Robert W.
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