Process for producing a vaccine for a pathogenic RNA virus and p

Details Process for producing a vaccine for a pathogenic RNA virus and p Process for producing a vaccine for a pathogenic RNA virus and p

1986-10-02

1994-08-16

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

4241991, 4242071, 424816, 4242351, C12N 1509, A61K 3912

Patent

active

053386744

ABSTRACT:
A process for producing live, non-pathogenic, vaccines for the pathogens RNA turmor virus utilizes gene-altering technology to produce an altered genome which codes for the antigenic determinants of a pathogen, but has no genes coding for pathogenicity. The vaccine is the phenotypic expression of the altered genome. Specifically, an avian RNA tumor virus env gene is cloned into the non-pathogenic RNA virus RAV-O and the resulting recombinant product is replicated in host cells to provide a recombinant vaccine for the pathogen avian RNA tumor virus.

REFERENCES:
patent: 4593002 (1926-06-01), Dulbecco
patent: 4603112 (1986-07-01), Paoletti et al.
Cohen, J., Science, Nov. 1, 1991, p. 647.
Berman, P., et al., Nature, 345, 622-625 (1990).
Elliott, T., et al., Nature, 348, 195-197 (1990).
Winner, E., JPOS, Sep. 1988, pp. 608-615.
Girard, M., et al., PNAS USA, 88, 542-546 (1991).
Groopman, J., Nature, 349, 568-569 (1991).
"Dictionary of Biochemistry", J. Stenesh, p. 330 (1975).
Matthews et al., "Prospects for Development of a Vaccine Against HIV", pp. 313-325, Human Retroviruses, Cancer and AIDS.
Fujita et al., J. Virol., vol. 27(3), pp. 465-474 (1978).
Pagatsch et al., J. Virol., vol. 43(2), pp. 503-510 (1982).
Hughes, J. Viol., vol. 43(1), pp. 191-200 (1982).
Robinson et al., Chem. Abst., vol. 78(5), No. 26160n (1972).

Affiliated with

Also associated with

Rating

Process for producing a vaccine for a pathogenic RNA virus and p does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for producing a vaccine for a pathogenic RNA virus and p, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for producing a vaccine for a pathogenic RNA virus and p will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-951425