Process for the preparation of solid drug formulations

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Polymer from ethylenic monomers only

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424247, 424274, 424326, A61K 934

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active

043159095

ABSTRACT:
In order to allow for the greatest possible range of variation in the rate of liberation of active agents within an organism and to allow for the use of a wide variety of active agents in solid drug formulations, cellulose graft copolymers are employed as adjuvant. The excellent flow properties and compacting behavior of these cellulose graft copolymers allow for formulation without the need for additional process steps, while variations in the type and proportion of the grafted components allows for the synthesis of adjuvants ideally suited for a specific intended use.

REFERENCES:
patent: 4115537 (1978-09-01), Driscoll et al.
The Merck Index, Ninth Edition, pp. 4073, 7019, 7234, (1976).
Gutbauer et al., Osterr., Chemiker Zeitung, vol. 67 (10), pp. 349-361, (1966).
Drawe, Angewandte Strahlenchemie, pp. 63-82, Dr. Huthig-Verlag Heidelberg, (1973).

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