Pyrazoloquinolines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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5142365, 544126, A61K 31535, C07D48704

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active

055978215

ABSTRACT:
The invention relates to compounds of the formulas ##STR1## wherein R.sub.1, R.sub.2, X and Z are as described herein. These compounds are useful as antitumor agents.

REFERENCES:
J. Biol. Chem., 261(24), 10963-65, 1986.
Nucleic Acids Research, vol. 17, No. 15(1989) pp. 6129-6141.
Townsend, Leroy, The Chemistry of Nucleosides and Nucleotides, Plenum Press, NY pp. 233-236, 1988.
JP 54157566 1979.
Chem. Lett. (1978) (6) pp. 605-608 (abstract).
J. Org. Chem. (1968) 33(5), 1806-10 (abstract).

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