Pyrazoloazepino substituted oximes useful as anti-atherosclerosi

Details Pyrazoloazepino substituted oximes useful as anti-atherosclerosi Pyrazoloazepino substituted oximes useful as anti-atherosclerosi

1995-06-06

1997-01-28

Spivack, Phyllis G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514214, 540476, 540593, A61K 3133, A61K 3155, C07D22314, C07D22504

Patent

active

055978169

ABSTRACT:
Pyrazoloazepino-substituted oximes, having the formula ##STR1## wherein R is ##STR2## where R.sup.5 is --(CH.sub.2).sub.c -- and c is 3-6 are disclosed. These compounds are useful for the treatment of atherosclerosis and hypercholesterolemia.

REFERENCES:
patent: 4327213 (1982-04-01), van Zorge
Almirante et al., J. Med Chem. 13(6) pp. 1048-1051 (1970).
Matyus et al., Chemical Abstracts, 92(15):128805h, (Apr. 14, 1980).

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