Preparation of 2-t-butyl-5-hydroxypyrimidine

Details Preparation of 2-t-butyl-5-hydroxypyrimidine Preparation of 2-t-butyl-5-hydroxypyrimidine

1981-09-14

1983-04-12

Coughlan, Jr., Paul M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544242, C07D23936

Patent

active

043799302

ABSTRACT:
The hydrolysis of 2-t-butyl-5-halopyrimidines is carried out in the presence of an alkali metal methoxide and a catalytic amount of an N-oxide, a disulfide or elemental sulfur to prepare 2-t-butyl-5-hydroxypyrimidine in good yields and purity.

REFERENCES:
patent: 3907797 (1975-09-01), Bodesinsky et al.

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