Methods for epi-retinal implantation

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Eye prosthesis

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128745, 128898, 607 53, 607116, 607118, A61F 214

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active

055973817

ABSTRACT:
A method for epi-retinal implantation of an object into a subject is disclosed. The method includes rendering the normally transparent cortical vitreous visible and separating at least a portion of a cortical vitreous of the subject away from an adherent retinal surface to form an epi-retinal space between the retina and the separated cortical vitreous material. An object to be implanted may be introduced into the epi-retinal space and the object engaged with a surface of the retina. In preferred embodiments, the object may then be adhered to the surface of the retina. A method for implantation of a neural contact structure for contact with neural tissue, for example, neural tissue of the retina within which are ganglion cells to be electrically stimulated is also described. The contact structure comprises a first portion for attachment to a first bodily location, such as the inner surface of the retina, and a second portion interconnected with the first portion via an interconnection and being held in contact with the neural tissue. The interconnection exhibits a weak restoring force which in conjunction with the geometry of said second portion provides a preselected desired pressure of contact against the neural tissue. As adapted for the retina, the interconnection exhibits a weak restoring force developed in response to curvature of the interconnection along the inner radius of the retina.

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B. Glaser, et al., "Transforming Growth Factor .beta.-2 for the Treatment of Full-thickness Macular Holes", Jan. 1992, Ophthalmology, vol. 99, pp. 1162-1173.
J. Vander, et al., "A Method for Induction of Posterior Vitreous Detachment During Vitrectomy", 1992, Retina, vol. 12, pp. 172-173.
H. Lincoff, et al., "Morphological Effects of Gas Compression on the Cortical Vitreous", Aug. 1986, Arch Ophthalmol., vol. 104, pp. 1212-1215.

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