Macrolide LHRH antagonists

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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C07C 6952

Patent

active

060205210

ABSTRACT:
Disclosed are 3'-N-desmethyl-3'-N-susbstituted-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythrolide A derivatives which are antagonists of luteinizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.

REFERENCES:
patent: 4677097 (1987-06-01), Omura et al.
Chem. Pharm. Bull. vol. 37. No. 10 (1989) pp. 2701-2709 T. Sunazuka et al. month not available.

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