NMR spectroscopy with phase encoding within a selected voxel

Electricity: measuring and testing – Particle precession resonance – Using a nuclear resonance spectrometer system

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G01R 3320

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active

049839209

ABSTRACT:
Magnetic resonance is excited in first selected dipoles and suppressed in second selected dipoles in an examination region (10) by the application of a binomial 90.degree. pulse (40). The induced resonance is phase encoded along at least two axes by phase encode gradients (42, 44). Concurrently, an RF refocussing pulse (54) and a slice select gradient pulse (56) are applied. Analogous pulse pairs (68, 70; 72, 74) are applied once with the slice select gradient along each of three mutual orthogonal axes such that a voxel or volume defined by the intersection of the three slices is defined. A magnetic resonance echo (84) is allowed to form, which echo is attributable to the resonating dipoles within the defined voxel. The phase encoding gradients have divided the voxel into subvoxels along the respective axes. The resultant magnetic resonance echo signals are Fourier transformed (92) into sets of chemical spectra corresponding to each subvoxel and displayed in a two dimensional image representation on a video monitor (96).

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Peter R. Luyten et al., NMR Spectroscopy of the Human Brain by Spatial Localization and Imaging Techniques, pg. 327.
T. Richards, et al., Phase Encoded Proton Spectroscopy and Imaging of the Rat Brain in Vivo with the Surface Coil, 1984, pp. 621-622.

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