Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1988-12-23
1991-01-08
Shah, Mukund I.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514248, 544115, 544234, 549 23, 549401, C07D49504, C07D49105, A61K 31535, A61K 3150
Patent
active
049836030
ABSTRACT:
The invention relates to novel tricyclic derivatives which are agonists of cholinergic receptors.
These derivatives have the formula ##STR1## in which X=O, S, --OCH.sub.2 -- or --SCH.sub.2 --; R.sub.1 =H or halogen; and R.sub.2 = ##STR2## in which Alk is an alkylene group and R.sub.3, an R.sub.4, which are identical or different, are hydrogen or a lower alkyl group, or R.sub.3 and R.sub.4, with the nitrogen atom to which they are bonded, form a 5- or 6-membered cyclic amino group optionally containing a second heteroatom; or R.sub.2 is a group ##STR3## where R.sub.5 =C.sub.1 -C.sub.4 -alkyl. Application: agonists of cholinergic receptors.
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Bourguignon Jean-Jacques
Brodin Roger
Wermuth Camille G.
Worms Paul
Bernhardt E.
Shah Mukund I.
Societe Anonyme: Sanofi
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