Nucleic acid multimers and amplified nucleic acid hybridization

Details Nucleic acid multimers and amplified nucleic acid hybridization Nucleic acid multimers and amplified nucleic acid hybridization

1989-04-18

1992-06-23

Wax, Robert A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435810, 436501, 935 23, 935 78, 935 88, 536 27, C12Q 168, C07H 2100

Patent

active

051242460

ABSTRACT:
Linear or branched oligonucleotide multimers useful as amplifiers in biochemical assays which comprise (1) at least one first single-stranded oligonucleotide unit that is complementary to a single-stranded oligonucleotide sequence of interest, and (2) a multiplicity of second single-stranded oligonucleotide units that are complementary to a single-stranded labeled oligonucleotide. Amplified sandwich nucleic acid hybridizations and immunoassays using the multimers are exemplified.

REFERENCES:
patent: 4358535 (1982-11-01), Falkow et al.
patent: 4670379 (1987-06-01), Miller
patent: 4683202 (1987-07-01), Mullis
patent: 4687732 (1987-08-01), Ward et al.
patent: 4689295 (1987-08-01), Taber et al.
patent: 4734363 (1988-03-01), Dattagupta et al.
patent: 4797355 (1989-01-01), Stabinsky
patent: 4800159 (1989-01-01), Mullis et al.
patent: 4808519 (1989-02-01), Hartley et al.
patent: 4808520 (1989-02-01), Dattagupta et al.
patent: 4828979 (1989-05-01), Klevan et al.
Kiyama et al. (1986) Proc. Natl Acad Sci (USA) vol. 83, pp. 4665-4669.
Stanley et al., (1987) Nature 274:87-89.
Wilson et al., (1985) Gene Anal Techn 2:77-82.
Ouellette et al., (1987) Can J Microbiol 33:205-211.
Bell et al., (1983) Analyt Biochem 130:527-535.
Sekine et al., (1985) Nucleic Acids Res 16:185-188.
Ma et al., (1986) Nucleic Acid Res 14:9745-9753.
Tomalia et al., (1986) Macromolecules 19:2466-2468.
Padias et al., (1987) J Org Chem 52:5305-5312.
Tomalia et al., (1987) Macromolecules 20:1164-1167.
Tomalia et al., (1987) J Am Chem Soc 109:1601-1603.
Newkome et al., (1986) J Chem Soc, Chem Commun 118:752-753.
Welcher et al., (1986) Nucleic Acids Research 14:10027-10044.
Urdea et al., (1987) Gene 61:253-264.
Worthy, Ward (Feb. 22, 1988) C&EN:19-21.
Naylor et al., (1989) J Am Chem Soc 111:2339-2341.
Posnett et al., (1988) J Biol Chem 263:1719-1725.
Guo et al., (1989) Biochemistry 28:2355-2359.
Lim et al., (1989) Cell 56:891-904.
Foldesi et al., (1989) Tetrahedron Letters 30:881-884.
Zhou et al., (1988) Tetrahedron 44:6471-6489.
Balgobin et al., (1988) Tetrahedron 44:6929-6939.
Damha et al., (1988) J Org Chem 53:3710-3722.
Huss et al., (1988) J Org Chem 53:499-506.
Petrillo et al., in Biopolymers vol. 27:1337-1352 John Wiley & Sons, Inc. (1988).

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