Anti-ulcer thiazoline derivatives

Details Anti-ulcer thiazoline derivatives Anti-ulcer thiazoline derivatives

1977-07-11

1979-03-06

Turner, V. D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

2603067T, A61K 31425

Patent

active

041431480

ABSTRACT:
4-Aryl-4-hydroxythiazolines can be obtained by treatment of aroylmethyl bromides with thiourea or a N-(lower alkyl)thiourea. The hydroxythiazolines are believed to have the formula ##STR1## where Ar is aryl and R is hydrogen or lower alkyl. The compounds are also capable of existing in open chain tautomeric form. The compounds show anti-ulcer activity in mammals.

REFERENCES:
patent: 3652577 (1972-03-01), Manning
Shadbolt, "J. Chem. Soc. .COPYRGT.", 1971, pp. 1667-1669.

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