Preparation of sterile products

Details Preparation of sterile products Preparation of sterile products

1975-08-26

1978-08-08

Hart, Charles N.

Liquid purification or separation

With alarm, indicator, register, recorder, signal or...

Responsive to fluid flow

210 65, 210 68, B01D 1700

Patent

active

041055500

ABSTRACT:
A sterile product is to be prepared from a substance which is dissolved in a solution. The first step in the preparation consists of subjecting the solution to a sterilizing filtration. Thereafter, the substance dissolved in the solution is precipitated therefrom under sterile conditions and the precipitate separated from the filtrate by means of a rotary disc filter which is located in a previously sterilized, closed chamber. Subsequent to the filtration, a dry, sterile gas is passed through the precipitate on the filter to dry it and the filter is then set into rotation so that a centrifugal force acts on the precipitate and causes it to be removed from the filter. The resulting product, which is completely sterile, is then immediately placed in a container. An arrangement for carrying out the above process is also disclosed.

REFERENCES:
patent: 3233734 (1966-02-01), Muller
Remington's Pharmaceutical Sciences, Mortin, 13th Ed., 1965, Mack Pub. Co., pp. 516-517, 478-479, 365-366, 332-333.

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