Sulfoxide-carboxylate intermediates of omeprazole and lansoprazo

Details Sulfoxide-carboxylate intermediates of omeprazole and lansoprazo Sulfoxide-carboxylate intermediates of omeprazole and lansoprazo

1994-11-22

1996-03-26

Fan, Jane

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D40112

Patent

active

055021956

ABSTRACT:
Omeprazole and lansoprazole, which are chemically pyridine-benzimidazole sulfinyl compounds, are produced from the corresponding acetamide-sulfide compounds by a process of oxidation to form the amide sulfinyl compound, followed by alkaline hydrolysis to the sulfinyl carboxylate or salt, and decarboxylation.

REFERENCES:
patent: 4255431 (1987-03-01), Junggren et al.
patent: 4628098 (1986-12-01), Nohara et al.
Doll et al. CA95:13286J 1981.

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