Process for making oligosaccharides having anti-Xa activity and

Details Process for making oligosaccharides having anti-Xa activity and Process for making oligosaccharides having anti-Xa activity and

1980-10-06

1983-08-30

Brown, Johnnie R.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

424180, 424183, 536 187, 536 21, 536 553, C12P 1926, C08B 3710, C07H 506

Patent

active

044017588

ABSTRACT:
Oligosaccharides obtainable from heparin including heparinic constituents of molecular weights ranging from 2000 to 50,000. Said fractions have a Yin-Wessler titer and a USP titer in a ratio of at least 30.
They consist of chains substituted by no more than 8 saccharidic moities. They possess a strong antithrombotic activity and are then useful as antithrombotic drugs.

REFERENCES:
patent: 3506642 (1970-04-01), Koh et al.
patent: 3985871 (1976-10-01), Butti et al.
patent: 4122250 (1978-10-01), Schmer
patent: 4175182 (1979-11-01), Schmer
patent: 4213962 (1980-07-01), Miura et al.
patent: 4281108 (1981-07-01), Fussi

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