Process for measuring microbiologically active material

Details Process for measuring microbiologically active material Process for measuring microbiologically active material

1981-01-29

1983-08-30

Warden, Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

435 32, 435 39, 435291, 435808, 435 29, C12Q 104, C12Q 118, C12Q 106, C12M 134

Patent

active

044017553

ABSTRACT:
The activity of a microbiologically active material is measured by suspending the material in a liquid medium capable of forming a gel. The resultant suspension is formed into small liquid droplets which droplets are caused to gel. The gel microdroplets (GMDs) are treated to effect desirable alteration of the microbiologically active material and the amount of metabolites or reaction products of the desired alteration within each get droplet is measured. Alternatively, incubation is carried out such that each GMD initially containing one cell contains many, a microcolony, which can be tested for desirable properties while retaining sufficient viable cells for with growth and harvesting for further testing and/or production.

REFERENCES:
patent: 3560754 (1971-02-01), Kamentsky
patent: 3710933 (1973-01-01), Fulwyler et al.
patent: 3790492 (1974-02-01), Fulwyler
patent: 4162282 (1979-07-01), Fulwyler et al.
patent: 4242447 (1980-12-01), Findl et al.

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