Method of using isotropic, porous-wall polymeric membrane, hollo

Details Method of using isotropic, porous-wall polymeric membrane, hollo Method of using isotropic, porous-wall polymeric membrane, hollo

1983-05-04

1984-04-10

Jones, Raymond N.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

435161, 435171, 435174, 435183, 435284, 435813, C12P 2100, C12N 900, C12M 300

Patent

active

044422067

ABSTRACT:
Hollow fiber reactors for growing microbial cells. Isotropic hollow fibers are supported in a housing inoculated with cells. Nutrient medium passing through the lumen undergoes a pressure drop resulting in radial convective flow: the nutrient medium flows outwardly from the lumen into the surrounding area adjacent the entry port and fluid surrounding the hollow fiber flows into the lumen adjacent the exit port. With the efficient distribution of nutrients and removal of product, high cell densities are achieved providing for high product yields per unit reactor volume.

REFERENCES:
patent: 3580840 (1971-05-01), Uridil
patent: 3767790 (1973-10-01), Guttag
patent: 3827565 (1974-08-01), Matsumura
patent: 3883393 (1975-05-01), Knazek et al.
patent: 3911140 (1975-10-01), Osborne et al.
patent: 4266026 (1981-05-01), Breslau
patent: 4391912 (1983-07-01), Yoshida et al.
Kan et al., "Urocanic Acid Production Using Whole Cells Immobilized on a Hollow-Fiber Reactor", Biotech. & Bioeng., vol. 20, pp. 271-320, 1978.
Webster et al., Biotechnology and Bioengineering, vol. 21, Abstract, pp. 1725-1748, 1979.
Webster et al., Biotechnology and Bioengineering, vol. 20, Abstract, pp. 1541-1556, 1978.
Webster et al., Chemical Engineering Science, vol. 34, 1979, pp. 1273-1282.
Porter, M. C., Biotechnology and Bioengineering Symposium No. 3, "Applications of Membranes to Enzyme Isolation and Purification", 1972, pp. 115-130.

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