Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1986-07-08
1988-11-01
Rotman, Alan L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
548194, 548195, 548119, C07D27744, C07D41712
Patent
active
047821582
ABSTRACT:
The present invention involves certain thiazol-4-yl-acetic acid compounds which are valuable intermediates for the preparation of cephem antibiotics. Said intermediates have the following structure: ##STR1## wherein R.sup.1 is an amino or a protected amino group; R.sup.2 is a group of the formula 13 CONH--R.sup.5 or --NHCO--R.sup.5 wherein R.sup.5 is pyridyl, thiazolyl or an isoxazolyl ring having lower alkyl and halogen substituted phenyl substituents, and A is lower alkylene, or a non-toxic salt thereof.
REFERENCES:
patent: 4203899 (1980-05-01), Ochiai et al.
patent: 4278793 (1981-07-01), Durckheimer et al.
Kamiya Takashi
Nakai Yoshiharu
Tanaka Kunihiko
Teraji Tsutomu
Fujisawa Pharmaceutical Co. Ltd.
Rotman Alan L.
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