Preparation of small bio-compatible microspheres

Details Preparation of small bio-compatible microspheres Preparation of small bio-compatible microspheres

1975-11-24

1979-02-06

Anderson, Harold D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

526227, 526303, 526320, 526328, 260 8, C08F 218, C08F 434

Patent

active

041383834

ABSTRACT:
Small, round, bio-compatible microspheres capable of covalently bonding proteins and having a uniform diameter below about 3500 A are prepared by substantially instantaneously initiating polymerization of an aqueous emulsion containing no more than 35% total monomer including an acrylic monomer substituted with a covalently bondable group such a hydroxyl, amino or carboxyl and a minor amount of a cross-linking agent.

REFERENCES:
patent: 3220960 (1965-11-01), Wichterle
patent: 3496254 (1970-02-01), Wichterle
patent: 3663467 (1972-05-01), Albright
patent: 3669089 (1972-10-01), Wichterle
patent: 3767600 (1973-10-01), Albright
patent: 3957741 (1976-05-01), Rembaum et al.

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