Synergistic effect of insulin-like growth factor-I and erythropo

Details Synergistic effect of insulin-like growth factor-I and erythropo Synergistic effect of insulin-like growth factor-I and erythropo

1995-02-03

1998-11-17

Weimar, Elizabeth C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 12, A61K 3830, A61K 3842, A61K 3800, C07K 1400

Patent

active

058376755

ABSTRACT:
Erythropoietin (EPO) and insulin-like growth factor (IGF); pharmaceutical compositions thereof and therapeutic and prophylactic methods to increase the hematocrit are disclosed herein. Increase in hematocrit and reticulocyte count is observed by IGF-I treatment alone or in combination with an other cytokine or growth factor. Also disclosed is the synergistic effect of EPO and IGF-I on hematocrit and reticulocyte count, and the use thereof for treating disease associated with a low erythropoietin level.

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