Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase
Patent
1985-05-06
1988-01-05
Warden, Robert J.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving hydrolase
C12Q 146
Patent
active
047176598
ABSTRACT:
In a method for determining cholinesterase (hereinafter referred to as ChE) activity, the improvement comprising by using, as a substrate, a protocatechuoylcholine derivative represented by the general formula (I), ##STR1## (wherein X is a halogen atom). The method for determining ChE activity according to the present invention is free from defects of the conventional methods, has many advantages and characteristics, permits accurate and simple determination of ChE activity, and can sufficiently contribute to determination of ChE activity in daily clinical examinations.
REFERENCES:
patent: 4565780 (1986-01-01), Motonaga et al.
S. Clausen et al., "Sep'n of Aromatic Choline Esters by High-Perf. Liquid Chromatog.," J. Chromatog., vol. 260 (1983), pp. 193-199.
Consera I. Nissui Pharmaceutical Co. Ltd., Tokyo, Japan.
Precipath E, Boehringer Mannheim, Mannheim, West Germany
Katayama Katsuhiro
Kuroiwa Katsumasa
Nagasawa Takeshi
Takabayashi Katsuyuki
Deck Randall E.
Lewen Bert J.
Nitto Boseki Co. Ltd.
Sternberg Henry
Warden Robert J.
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