New heteroarotinoid compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549408, 549398, 549 60, 549 57, 548525, 548454, 546269, 546196, 544332, 544328, 544322, 544151, 544 62, 514444, 514443, 514422, 514414, 514337, 514320, 514256, 5142315, 5142278, A61K 3135, C07D31158

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049754556

ABSTRACT:
Compounds of general formula (I): ##STR1## in which: R denotes a hydrogen atom, a halogen atom or a hydroxy, lower alkyl, lower alkyloxy, carboxyl, (lower alkyloxy)carbonyl, (lower arylalkyloxy)carbonyl, aminocarbonyl, (lower mono- or dialkyl)aminocarbonyl or (lower arylalkyl)aminocarbonyl group, an aminocarbonyl group N-substituted with a heterocyclic radical, or a thio, (lower alkyl)thio, sulfonyl or (lower alkyl)sulfonyl group,

REFERENCES:
patent: 4808597 (1989-02-01), Hoffman et al.
patent: 4826984 (1989-05-01), Berlin et al.
Suffness et al., J. Nat. Prod., 45, 1 (1982).
The Lancet, Apr. 16, 1983, pp. 860 through 863, "Nutrition: The Changing Scene".

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