Process for the production of 1,2,4-triazin-5-one derivatives

Details Process for the production of 1,2,4-triazin-5-one derivatives Process for the production of 1,2,4-triazin-5-one derivatives

1978-07-12

1979-11-20

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C07D25306

Patent

active

041751884

ABSTRACT:
1,2,4-triazin-5-one compounds of the general formula (I) ##STR1## where R is ##STR2## are prepared by reacting a compound of general formula (II) ##STR3## in which R is defined above with either (a) a tertiary alcohol of general formula (III)

REFERENCES:
patent: 4013649 (1977-03-01), Bogdanowicz
patent: 4057417 (1977-11-01), Dickore et al.
patent: 4058525 (1977-11-01), Hofer et al.
patent: 4058526 (1977-11-01), Merz et al.
patent: 4113767 (1978-09-01), Merz
Thesing et al., "Die Chemie der Acylcyanide", Angewandte Chemie, vol. 68, pp. 425-435 (1956).
Ugi et al., Chem. Ber., vol. 94, pp. 1116-1121 (1961).
Ritter et al., J. Amer. Chem. Soc., vol. 70, pp. 4045-4050 (1948).
Hurd et al., J. Amer. Chem. Soc., vol. 66, pp. 2013-2014 (1944).
Dornow et al., Chem. Berichte, vol. 97, pp. 2173-2178 (1964).

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