Compositions and methods for the synthesis of chirally pure orga

Details Compositions and methods for the synthesis of chirally pure orga Compositions and methods for the synthesis of chirally pure orga

1996-08-29

1999-01-05

Wilson, James O.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 2531, 536 2532, 536 2534, 536 254, 536 2541, 536124, 536125, 536126, C07H 2100, C07H 100

Patent

active

058564659

ABSTRACT:
Methods for the stereospecific synthesis of chirally pure organophosphorus dinucleotide derivatives and nucleoside monomer synthons used in their synthesis are provided. These methods allow for conversion of nucleoside intermediates of unchosen sense of P-chirality to nucleoside monomer synthons of chosen sense of P-chirality. Also provided are novel nucleoside intermediates useful in such methods.

REFERENCES:
patent: 5359052 (1994-10-01), Stec et al.
patent: 5512668 (1996-04-01), Stec et al.
patent: 5646267 (1997-07-01), Stec et al.

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