Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1978-05-01
1980-06-10
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
2602452, 2602453, 548324, 424273R, 424271, A61K 3138, C07D49900
Patent
active
042073235
ABSTRACT:
Disclosed are antibiotic 6-(substituted methyl) penicillins, derivatives and nuclear analogues thereof; wherein the methyl substituent is, inter alia, hydroxyl, ketonic oxygen, imino nitrogen, amino or thio. Also disclosed are processes for the preparation of such compounds and their pharmaceutically acceptable salt, ester and amide derivatives; pharmaceutical compositions comprising such compounds; and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.
REFERENCES:
patent: 3174964 (1965-03-01), Hobbs et al.
patent: 3809700 (1974-05-01), Rapoport
patent: 4000154 (1976-12-01), Gleason et al.
Beattie Thomas R.
Christensen Burton G.
DiNinno Frank P.
Anderson, Jr. Rudolph J.
Daus Donald G.
Levitt Julian S.
Mahon Frank M.
Merck & Co. , Inc.
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